Set to be built on the Gulf of Aqaba coast in northwestern Saudi Arabia, Epicon is the sixth of Neom's planned 10 regions to be announced.
It will be designed by architecture studio 10 Design and comprise two jagged towers, one measuring 225 and the other 275 metres, which will contain 41 hotel and luxury residences.
The steel-clad skyscrapers are visualised as being interconnected by horizontal levels that hold an outdoor pool, among other spaces.
The region will also be home to the Epicon resort, which will have 120 rooms as well as 45 beach villas. Among the amenities on offer will be a beach club, spa and restaurants.
"Designed as a gateway to the future, Epicon provides an opportunity to escape the stresses of the everyday," Neom said.
"Whether relaxing at the beach club, visiting the spa for bespoke wellness treatments, exploring the surrounding nature, participating in one of the many watersports on offer, or dining at destination restaurants for an unforgettable culinary experience, Epicon has been conceived to meet the full array of guest and resident needs."
The resort will also have a library and a gym as well as pools, lounges and workspaces.
Epicon was created by 10Design
The unveiling of Epicon follows the announcement of Neom's fifth region, Leyja, which will also house high-end boutique hotels and include designs by Shaun Killa, Mario Cucinella and Chris van Duijn.
The Neom project will contain 10 regions in total, including the controversial The Line project – a linear mega-city that will be 170 kilometres long. It will also include an octagon-shaped port city named Oxagon, the mirrored mega-city The Line and an island resort called Sindalah.
However, the project has been criticised on human rights grounds, including by human rights organisation ALQST which reported that three men were sentenced to death after being "forcibly evicted" from the Neom site.
Earlier this year experts from the UN Human Rights Council expressed "alarm" over the imminent executions. Saudi Arabia responded to the UN by denying abuses had taken place.
In an opinion piece for Dezeen about The Line mega project, Dana Cuff wondered "Why would architects let themselves be so vitiated?"
The images are courtesy of Neom.